Others you'll be thick in the mix of a zombie swarm and frantically calling out for your teammate to heal you both. Some areas you'll simply find yourself so over run it's best just to sit back and try to pick off the enemy while your partner covers you, but keep an eye on the interface for clues when they'll need assistance. Your best bet is picking a few weapon types for each character and sticking with it, this way you can spread the wealth of ammo pickups between each other as you find them.
Team work is crucial throughout the game as ammo is limited.